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 Formulary Chapter 6: Endocrine system - Full Chapter
06.01.01.02  Expand sub section  Intermediate- and long-acting insulins
Insuman Basal®
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First Choice
Green
Vial, Cartridge + ClikSTAR, SoloStar 
Humulin I®
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Second Choice
Green
Intermediate Human Isophane
Vial, Cartridge + HumaPen Savvio, KwikPen 
   
Insulatard®
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Restricted Drug Restricted
Green
Intermediate Human Isophane
For use only when the Innolet device is required. Restricted to patients not able to manage less expensive devices 
   
Lantus®
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Formulary
Green
Insulin Glargine 100 unit per ml
MUST BE PRESCRIBED BY BRAND NAME
Recombinant human insulin analogue- long acting. Monophasic. Once daily dosage

Vial, Cartridge+ClikSTAR, SoloStar 
   
Abasaglar®
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Formulary
Green
A Biosimilar of Insulin Glargine.
MUST BE PRESCRIBED BY BRAND NAME
Recommended in LLR for new patients and those undergoing review of therapy. 
Link  Statement on Use of Biosimilar Insulin
   
Levemir®
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Formulary
Green
Insulin Detemir.
Recombinant human insulin analogue – long acting. Monophasic. Twice daily dosing
Cartridge + NovoPen 4, Flexpen
Innolet also available but only for patients not able to manage less expensive device 
   
Toujeo®
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Formulary
Green Conditional

Insulin Glargine 300 units per ml.
MUST BE PRESCRIBED BY BRAND NAME
First line concentrated insulin of choice in insulin resistant patients requiring large amounts of insulin. Please take extra care in prescribing, insulin glargine 300units per ml and 100units per ml are not directly interchangeable - see SPC

 
Link  Leicestershire Evaluation: Toujeo® in Diabetes
Link  UKMI - Product Safety Assessment Report
   
Tresiba®
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Restricted Drug Restricted Insulin Degludec
For use in specific patient groups only in line with agreed algorithm.
  • Conditional Green traffic light status for GPs who have completed appropriate training.
  • Amber traffic light status for those without additional training.
     
  • Link  Leicestershire Evaluation: Insulin Degludec in Diabetes
    Link  Simple Amber list
    Link  Tresiba (Insulin Degludec) 100 units per ml: patient selection criteria
    Link  Tresiba (Insulin Degludec) 200 units per ml: patient selectin criteria
       
    06.01.01.02  Expand sub section  Biphasic insulins
    Humulin® M3
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    First Choice
    Green
    30/70 soluble / isophane
    Vial, Cartridge + HumaPen Savvio, KwikPen 
    Humalog® Mix25, Humalog®Mix50
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    Formulary
    Green
    Biphasic Insulin Lispro. Analogue insulin
    Vial, Cartridge + HumaPen Savvio, KwikPen 
       
    NovoMix® 30
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    Formulary
    Green
    Biphasic Insulin Aspart. Analogue insulin.
    Cartridge + NovoPen 4, Flexpen 
       
     ....
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    SMC
    Scottish Medicines Consortium
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Black

    Drugs not recommended for use in the Leicestershire Health Community because of lack of evidence of clinical effectiveness, cost prioritization or concerns over safety. All new drugs will be black until they have been through the appropriate approval process - then they will appear as a specific entry   

    Red

    Drugs which should be prescribed only by hospital specialists (clinical review by specialist as appropriate and annually as a minimum).  

    Amber SCA

    Drugs which would initially be prescribed by a hospital specialist and then by a GP where full agreement to share the care of each specific patient has been reached under a LMSG Shared Care Agreement (SCA). Specific patient monitoring or intervention required.   

    Amber Simple

    Drugs suitable to be initiated and prescribed in primary care only after specialist assessment and recommendation. A shared care agreement is not required.  

    Green Conditional

    Drugs for which GPs are able to take full responsibility for prescribing and monitoring subject to specified conditions e.g. prescribing in line with agreed LMSG guidance or able to demonstrate suitable competence see comments under individual entries.   

    Green

    Drugs for which GPs would normally take full responsibility for prescribing and monitoring. Drugs included in this list have been specifically considered by LMSG.   

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