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 Formulary Chapter 5: Infections - Full Chapter
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05.03.01  Expand sub section  HIV infection
05.03.01  Expand sub section  Nucleoside reverse transcriptase inhibitors
Abacavir
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Restricted Drug Restricted
Red
High Cost Medicine
 
   
Abacavir and Lamivudine (Kivexa)
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff 
   
Bictegravir, Emtricitabine and Tenofovir Alafenamide (Biktarvy)
View adult BNF View SPC online  Track Changes
Restricted Drug Restricted
Red

High cost drug excluded to tariff
Restricted, to be used in line with NHSE policy only

 
   
Didanosine
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff 
   
Efavirenz, Emtricitabine and Tenofovir Disoproxil (Atripla)
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff  
   
Elvitegravir, Cobicistat, Emtricitabine and Tenofovir Alafenamide  (Genvoya)
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff  
Link  MHRA advice: Cobicistat, ritonavir and coadministration with a steroid: risk of systemic corticosteroid adverse effects
Link  MHRA Advice: Elvitegravir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure
Link  NHSE Policy: Tenofovir Alafenamide
   
Elvitegravir, Cobicistat, Emtricitabine and Tenofovir Disoproxil  (Stribild)
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Restricted Drug Restricted
Red
High Cost Medicine
 
Link  MHRA advice: Cobicistat, ritonavir and coadministration with a steroid: risk of systemic corticosteroid adverse effects
Link  MHRA Advice: Elvitegravir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure
Link  NHSE Policy: Stribild
   
Emtricitabine
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff 
   
Emtricitabine and Tenofovir Alafenamide (Descovy)
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Restricted Drug Restricted
Red
High Cost Medicine
High cost drug excluded to tariff
Restricted, to be used in line with NHSE policy only 
Link  NHSE Policy: Tenofovir Alafenamide
   
Emtricitabine, Rilpivirine and Tenofovir Alafenamide (Odefsey)
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Restricted Drug Restricted
Red
High Cost Medicine
High cost therapy excluded to tarrif
Restricted, to be used in line with NHSE policy only 
Link  NHSE Policy: Tenofovir Alafenamide
   
Emtricitabine, Rilpivirine and Tenofovir Disoproxil  (Eviplera)
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff
Only for those intolerant or non responsive to Atripla 
   
Lamivudine
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff
Also used in treatment of Hepatitis B, commissioned by NHSE in line with NICE CG165 only
 
Link  NICE CG165: Hepatitis B (chronic): Diagnosis and management of chronic hepatitis B in children, young people and adults
   
Tenofovir Disoproxil
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff 
   
Tenofovir Disoproxil and Emtricitabine (Truvada)
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Drug excluded to tariff  
   
Zidovudine
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff 
   
Zidovudine and Lamivudine
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Restricted Drug Restricted
Red
High Cost Medicine
High Cost Therapy excluded to tariff
Generic combination has a lower cost than the individual components prescribed separately 
   
Darunavir, Cobicistat, Emtricitabine and tenofovir alafenamide (Symtuza)
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Restricted Drug Restricted
Red
NHS England

High cost drug excluded to tariff. Restricted, to be used in line with NHSE policy only

 
Link  NHSE Commissioning Policy: Clinical Commissioning Policy: Use of cobicistat as a booster in treatment of HIV infection
   
05.03.01  Expand sub section  Protease inhibitors
05.03.01  Expand sub section  Other antiretrovirals
 ....
 Non Formulary Items
Stavudine

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Non Formulary
Black
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Black

Drugs not recommended for use in the Leicestershire Health Community because of lack of evidence of clinical effectiveness, cost prioritization or concerns over safety. All new drugs will be black until they have been through the appropriate approval process - then they will appear as a specific entry   

Red

Drugs which should be prescribed only by hospital specialists (clinical review by specialist as appropriate and annually as a minimum).  

Amber SCA

Drugs which would initially be prescribed by a hospital specialist and then by a GP where full agreement to share the care of each specific patient has been reached under a LMSG Shared Care Agreement (SCA). Specific patient monitoring or intervention required.   

Amber Simple

Drugs suitable to be initiated and prescribed in primary care only after specialist assessment and recommendation. A shared care agreement is not required.  

Green Conditional

Drugs for which GPs are able to take full responsibility for prescribing and monitoring subject to specified conditions e.g. prescribing in line with agreed LMSG guidance or able to demonstrate suitable competence see comments under individual entries.   

Green

Drugs for which GPs would normally take full responsibility for prescribing and monitoring. Drugs included in this list have been specifically considered by LMSG.   

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