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Medicines Formulary  
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 Formulary Chapter 4: Central nervous system - Full Chapter
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04.02.03  Expand sub section  Drugs used for mania and hypomania
 note  Olanzapine is also licensed for treatment of mania
Carbamazepine
View adult BNF View SPC online  Track Changes
Restricted Drug Restricted Specialist in Psychiatry Initiation only. 
Link  Leicestershire Guidance: Antiepileptics and Bone Mineral Density
Link  Toxicology and Therapeutic Dose Monitoring
   
Lithium
View adult BNF View SPC online  Track Changes
Restricted Drug Restricted
Amber SCA
Specialist in Psychiatry Initiation only. BNF recommends to prescribe by brand. Priadel is the brand recommended for new patients due to cost. 
Link  Leicestershire Guidelines: Lithium in Acute and Primary Care Settings
Link  NPSA alert: Safer Lithium Therapy
Link  SCA: Lithium
Link  Toxicology and Therapeutic Dose Monitoring
   
Semisodium Valproate (Depakote)
View adult BNF View SPC online  Track Changes
Restricted Drug Restricted
Amber Simple
Mania in bipolar disorder. Specialist in Psychiatry Initiation only. 
Link  Drug Safety Update: Valproate medicines (Epilim▼, Depakote▼)
Link  MHRA Guidance: Valproate use by women and girls
Link  Resources to Use: Booklet for Healthcare Professionals
Link  Resources to Use: Card to give to patients
Link  Resources to Use: Consultation Checklist
Link  Resources to Use: Guide to give to patients
Link  Topiramate and Valproate Flow Chart
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Black

Drugs not recommended for use in the Leicestershire Health Community because of lack of evidence of clinical effectiveness, cost prioritization or concerns over safety. All new drugs will be black until they have been through the appropriate approval process - then they will appear as a specific entry   

Red

Drugs which should be prescribed only by hospital specialists (clinical review by specialist as appropriate and annually as a minimum).  

Amber SCA

Drugs which would initially be prescribed by a hospital specialist and then by a GP where full agreement to share the care of each specific patient has been reached under a LMSG Shared Care Agreement (SCA). Specific patient monitoring or intervention required.   

Amber Simple

Drugs suitable to be initiated and prescribed in primary care only after specialist assessment and recommendation. A shared care agreement is not required.  

Green Conditional

Drugs for which GPs are able to take full responsibility for prescribing and monitoring subject to specified conditions e.g. prescribing in line with agreed LMSG guidance or able to demonstrate suitable competence see comments under individual entries.   

Green

Drugs for which GPs would normally take full responsibility for prescribing and monitoring. Drugs included in this list have been specifically considered by LMSG.   

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