netFormulary Leicestershire Health Community NHS
Medicines Formulary  
 Formulary Chapter 2: Cardiovascular system - Full Chapter
02.02.04  Expand sub section  Potassium-sparing diuretics with other diuretics
 note  Combined loop or thiazide diuretic with a potassium-sparing agent should not be used indiscriminately. They are more expensive than diuretic alone and are more likely to cause hyponatraemia or other adverse reactions than a single agent.
Co-amilofruse 5/40
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Amiloride 5mg with furosemide 40mg
Proprietary brands are more costly
Co-amilozide 5/50
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Amiloride 5mg with hydrochlorothiazide 50mg; (Moduretic) 
Link  MHRA advice: Hydrochlorothiazide: risk of non-melanoma skin cancer, particularly in long-term use
 Non Formulary Items

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Non Formulary
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Track Changes
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Scottish Medicines Consortium
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHS England

Traffic Light Status Information

Status Description


Drugs not recommended for use in the Leicestershire Health Community because of lack of evidence of clinical effectiveness, cost prioritization or concerns over safety. All new drugs will be black until they have been through the appropriate approval process - then they will appear as a specific entry   


Drugs which should be prescribed only by hospital specialists (clinical review by specialist as appropriate and annually as a minimum).  

Amber SCA

Drugs which would initially be prescribed by a hospital specialist and then by a GP where full agreement to share the care of each specific patient has been reached under a LMSG Shared Care Agreement (SCA). Specific patient monitoring or intervention required.   

Amber Simple

Drugs suitable to be initiated and prescribed in primary care only after specialist assessment and recommendation. A shared care agreement is not required.  

Green Conditional

Drugs for which GPs are able to take full responsibility for prescribing and monitoring subject to specified conditions e.g. prescribing in line with agreed LMSG guidance or able to demonstrate suitable competence see comments under individual entries.   


Drugs for which GPs would normally take full responsibility for prescribing and monitoring. Drugs included in this list have been specifically considered by LMSG.