Leicestershire Health Community
Medicines Formulary
 
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6 Endocrine system
06-03-02 Glucocorticoid therapy

Hydrocortisone sodium succinate injection
First Choice
For disease suppression

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Prednisolone
First Choice
For disease suppression.
Enteric coated tablets are not routinely stocked at UHL.
The potential advantage of soluble or enteric coated preparations to reduce the risk of gastric ulcers is speculative. They are considerably more costly.
Prednisolone soluble can be up to 200 times more costly than plain tablets depending on the setting. Plain tablets can be crushed and dispersed (unlicensed).


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Dexamethasone
Second Choice
For disease suppression. Preferred choice in cerebral oedema as it has less mineralocorticoid activity. Also used in vomiting associated with cancer chemotherapy.

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Methylprednisolone sodium succinate injection
Second Choice
For disease suppression when larger doses of corticosteroid are required.

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Prednisolone EC
Non Formulary

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