Leicestershire Health Community
Medicines Formulary
 
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3 Respiratory system
03-07 Mucolytics

Carbocisteine
Formulary

Mucolytics have limited value in COPD. May reduce exacerbations in some patients with chronic obstructive pulmonary disease and a chronic productive cough. Therapy should be stopped if there is no benefit after a 4-week trial. Please see carbocisteine guidance below. 

Link  Leicestershire Guidance: Prescribing of Carbocisteine capsules and liquid
 

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Dornase Alfa Pulmozyme®
Restricted
Classified Simple Amber in Leicestershire Traffic Lights
For cystic fibrosis.
High cost drug excluded to tariff. NHSE commissioned
Link  NHSE Commissioning Policy: Cystic Fibrosis Inhaled Therapies
Link  Simple Amber: Dornase Alpha (Pulmozyme®) in the treatment of Cystic Fibrosis
 

Restricted Drug Amber Simple View adult BNF  View SPC online
Mannitol
Restricted
High cost drug excluded to tariff. NHSE commissioned

Date of entry of decision to Formulary: February 2013
Link  NHSE Commissioning Policy: Cystic Fibrosis Inhaled Therapies
 

Restricted Drug Red View adult BNF  View SPC online
Ivacaftor
Restricted
High cost drug excluded to tariff. NHSE commissioned
Link  NHSE Policy: Ivacaftor in Cystic Fibrosis
 

Restricted Drug Red View adult BNF  View SPC online
Acetylcysteine
Non Formulary

Effervescent tablets and powder. Not supported for use by the Leicestershire Respiratory Group


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Erdosteine
Non Formulary

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Lumacaftor - Ivacaftor
Non Formulary
Not supported for use, negative NICE TA appraisal
Link  NICE TA 398: Lumacaftor–ivacaftor: Cystic Fibrosis
 

Black View adult BNF  View SPC online